Mode of transmisison: faecal oral route

Incubation: 1-3d

Period of infectivity: immediately before and up to 1-2wks after onset

Vaccines:  live attenuated  - orally administrated

• RV5 - pentavalent

Schedule: 6wk, 3mo, 5mo,

efficacy: highly effective against severe rotavirus

some efficacy against all cause diarrhoea and herd immunity

precaution; theoretically - intussusception

CI with acute or moderate GI

• double stranded RNA virus

Clinical

• infects almost all children

• up to 1/3 develop fever >39

• illness 3-8d